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Efficacy Data
The PureZone personal air filtration system is a stand-alone therapy that combines the benefits of localized HEPA filtration and pillow mite encasement to deliver effective allergen exposure reductions in any bedroom environment. In a randomized placebo controlled clinical trial of the PureZone system, consistent night-time allergen exposure reductions were demonstrated in the breathing zone, regardless of allergen sources in the bedroom (Figure 1).

Figure 1: Breathing zone particulate exposure reductions (n=35 subjects)

The study population was suffering from indoor allergen exposures (perennial allergic rhinoconjunctivitis), which were shown to be greatly reduced (>99.99%) with the active PureZone treatment resulting in multiple clinical benefits versus placebo including: improved quality of life and sleep; and relief of ocular and nasal symptoms (Figure 2)

Figure 2: Clinical benefits reported for multiple outcomes vs. placebo, including: total symptom scores (TSS), which was the summation of ocular and nasal allergy symptoms; Nasal symptoms, which was the summation of congestion, itch, sneeze, and rhinorohhea; Ocular symptoms, which measured ocular itch/watering; and, Noctournal rhinoconjunctivitis quality of life questionnaire (NRQLQ), which included symptom, quality of sleep, and productivity measures.

Trials of other personal air filtration systems have demonstrated compelling clinical benefits for asthmatic populations, benefits that include: reduced symptoms; improved quality of life; and reduced bronchial inflammation. The PureZone system clinical trial is the first study that extends these benefits to populations suffering from allergic diseases. Taken as a whole, the results of personal air filtration clinical trials suggest that these systems offer consistent clinical benefits for allergic and asthmatic patient populations. Compared to other avoidance options, personal air filtration systems are unique in that they are effective as stand-alone therapies; other avoidance measures often require a multi-faceted approach to achieve similar clinical benefits (Figure 3).

Figure 3: Review of Allergen Avoidance Measure Efficacy: Reported clinical benefits versus placebo for a select group of studies.

See all the details about the effectiveness of the PureZone personal air filtration system:

AAAAI Presentation by Dr. Allan Stillerman

ACAAI Presentation by Dr. Allan Stillerman

PureZone Clinically Proven (:57)
Dr. Allan Stillerman reviews the system's successful performance in a recent clinical trial.

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